NCT01442948已完成不适用
CD16+ Monocytes in Patients With Coronary Heart Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Absolute numbers of CD16+ monocytes stratified by tertiles related to the incidence of the combined endpoint
研究概览
简要总结
Monocytes may be separated into phenotypically and functionally distinct cell types by the presence or absence of the lipopolysaccharide receptor CD14 and the Fcγ-receptor CD16. The investigators hypothesize that the total numbers of CD16+ monocytes are significantly related to cardiovascular outcome in patients with angiographically proven coronary heart disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •angiographically proven coronary heart disease
- •Age > 18 years
排除标准
- •life expectancy < 12 months
- •inability to participate in the trial (to give written informed consent)
结局指标
主要结局
Absolute numbers of CD16+ monocytes stratified by tertiles related to the incidence of the combined endpoint
时间窗: 12 months
Incidence of the combined endpoint (non-fatal myocardial infarction, cardiovascular death, stroke) during a follow-up of 12 months
次要结局
- Absolute numbers of CD16+ monocytes stratified by tertiles related to the incidence of each part of the combined endpoint + total death(12 months)
- Subgroup analysis for absolute numbers of CD16+ monocytes stratified by tertiles in relation to the combined endpoint(12 months)
研究者
Axel Schlitt
Senior Physician
Martin-Luther-Universität Halle-Wittenberg
研究点 (1)
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