跳至主要内容
临床试验/CTRI/2025/05/087162
CTRI/2025/05/087162尚未招募不适用

Comparision of Septic Shock indices in Post - Congenital Cardiac Surgery sepsis in Infants- A single centre Prospective Longitudional study.

Dr Venuthurupalli SP Rajesh1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年6月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
To identify the association between Shock Index, Modified Shock Index and Diastolic Shock Index and outcome in Sepsis in infant Cardiac Surgery.

研究概览

简要总结

New surgical methods, increased perioperative care has caused a boost of congenital cardiac surgeries in third-world countries, leading to a greater number of infant congenital cardiac surgeries in underdeveloped countries because of the increase in infant  cardiac surgical procedures with better results, even though significant postoperative illnesses and mortality remain mainly because of sepsis. Initial resuscitation of shock is commonly guided by the normalization of hemodynamic and laboratory variables such as HR, BP, central venous pressure, and lactic acid. SI may be a good and non invasive measure of the degree of hemodynamic stability and may be used as an indicator of tissue perfusion. It has been shown to correlate with other indices of end‑organ perfusion such as central vena cava oxygen saturation and lactate concentration. We will examine if SI, DSI and MSI can be employed as a non-invasive tool to identify neonates with a heightened mortality risk than HR and BP in post-cardiac surgical patients with sepsis.

研究设计

研究类型
Observational

入排标准

年龄范围
29.00 Day(s) 至 1.00 Year(s)(—)
性别
All

入选标准

  • patients developing sepsis post congenital cardiac surgery and getting admitted in the recovery room.

排除标准

  • Patients less than 29 days, patients more than 1 year, patients with preoperative sepsis, patients not developing sepsis post operatively.

结局指标

主要结局

To identify the association between Shock Index, Modified Shock Index and Diastolic Shock Index and outcome in Sepsis in infant Cardiac Surgery.

时间窗: At baseline (0 hour), 1 hour, 2 hour and 6 hour.

次要结局

  • To diagnose sepsis using Tollner sepsis scoring system and EMA sepsis scoring system by measuring heart rate and blood pressure.(At baseline (0 hour), 1 hour, 2 hour and 6 hour.)

研究者

发起方
Dr Venuthurupalli SP Rajesh
申办方类型
Research institution
责任方
Principal Investigator
主要研究者

Dr Venuthurupalli SP Rajesh

UN Mehta Institute of Cardiology and Research Centre.

研究点 (1)

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