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临床试验/CTRI/2026/01/102085
CTRI/2026/01/102085尚未招募不适用

Predicting microbiome profile and other health related markers from metabolites

MicrobioTx Health Private Limited1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2026年2月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1

研究概览

简要总结

The vaginal microbiota assumes a pivotal role in maintaining vaginal health and the prevention of various illnesses. The microbial community of the vaginal flora is highly dynamic in nature, and tends to aggregate into distinct groups. Certain community types have been found to have a higher likelihood of leading to unfavorable reproductive outcomes. For example, populations that exhibit a predominance of Lactobacillus species, have been associated with better vaginal health. Vaginal microbiome has been studied in different indications such as Bacterial vaginosis, infertility, endometriosis etc. Despite recent studies highlighting the association of specific microbiome changes with infertility, vaginal infertility profiling remains limited in its adoption. Vaginal microbiome testing is very expensive, offered by limited players and is time consuming as it involves genomic sequencing.

研究设计

研究类型
Observational

入排标准

年龄范围
19.00 Year(s) 至 49.00 Year(s)(—)
性别
Female

入选标准

  • For Infertility group.
  • Married female patients of reproductive age group having an active married life (regular unprotected intercourse, minimum of 12 months) and with a complaint of being unable to conceive for 1 year. For the control group.
  • females with a history of at least 1 spontaneous conception and no current history of infertility.

排除标准

  • Participants with a history of alcohol consumption exceeding 20 grams per day Participants taking immunosuppressants, tamoxifen, amiodarone and/or perhexiline; Participants who have taken antibiotics in the last 3 weeks Current use of vaginal creams or pessary Inability to conceive due to male infertility Active genital or gastrointestinal infection Any active illness, psychological and/or pathological condition or chronic disease that would interfere with study participation in the opinion of the Investigator.

研究者

发起方
MicrobioTx Health Private Limited
申办方类型
Other [startup]
责任方
Principal Investigator
主要研究者

Dr Palok Aich

MicrobioTx Health Private Limited

研究点 (1)

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