跳至主要内容
MedPath Trial logoMedPath TrialMedPath Trial Home
临床试验/NCT05681325
NCT05681325进行中（未招募）不适用

Evaluation of Antioxidant and Anti-inflammatory Effect of Matcha Tea Intake on Periodontal Health

Hayder Raad Abdulbaqi1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年1月25日最近更新:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
适应症

试验速览

阶段
不适用
状态
进行中（未招募）
发起方
入组人数
40
试验地点
1
主要终点
change in salivary level of ant-inflammatory marker
研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Aim of the study:

This study aims to evaluate the antioxidant and beneficial effects of matcha tea daily intake on periodontal health.

Objectives:

  • To evaluate the salivary level of antioxidants (catalase, total antioxidant capacity) after matcha tea intake compared to green tea over a period of one month.
  • To evaluate the clinical periodontal parameters including bleeding on probing (BOP), probing pocket depth (PPD) and plaque index (PI) after matcha tea intake compared to green tea over a period of one month.
  • To evaluate the salivary levels of IL-1B after matcha tea intake compared to green tea over a period of one month.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 40 Years（Adult）
性别
All
接受健康志愿者
是

入选标准

  • •• having at least 20 teeth,
  • •underwent no medical treatment during the last 3 months before examination and sampling,
  • •non-smoker,
  • •no history of systemic disease,
  • •gingivitis patient (having >10% bleeding sites with no PPD >3 mm).

排除标准

  • •• wore orthodontic appliances,
  • •pregnant or currently in the breast-feeding period,
  • •periodontitis patient,
  • •has a history of systemic disease.

结局指标

主要结局

change in salivary level of ant-inflammatory marker

时间窗: 30 Days (baseline to one moth of tea intake)

change in level of interleukin- one beta (IL-1B) in pg/L

change in salivary level of antioxidant marker

时间窗: 30 Days (baseline to one moth of tea intake)

change in level of catalase enzyme in ku/L

次要结局

  • change in percentage of bleeding on probing (BOP)(30 Days (baseline to one moth of tea intake))
  • change in plaque index (PI) scores(30 Days (baseline to one moth of tea intake))

研究者

发起方
Hayder Raad Abdulbaqi
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Hayder Raad Abdulbaqi

professor

University of Baghdad

研究点 (1)

Loading locations...

相似试验

已完成
不适用
Antioxidant and Anti-inflammatory Effects of Yogurt Enriched With PolyphenolsOxidative StressInflammation
NCT02494739University of Thessaly18
已完成
2 期
To study the efficacy ofCurcuma longa extract in Osteoarthritis of knee patients.
CTRI/2015/12/006438Himalaya Drug Company160
已完成
不适用
Effects of Black Tea on Type 2 DiabetesType 2 Diabetes Mellitus
NCT00916188National Nutrition and Food Technology Institute45
已完成
不适用
Effects of supplementation with orally effective Superoxide Dismutase, GliSODin, on oxidative stress, inflammation and performance in athletesExercise performanceExercise induced oxidative stressExercise induced inflammationAlternative and Complementary Medicine - Other alternative and complementary medicineMusculoskeletal - Normal musculoskeletal and cartilage development and function
ACTRN12622000319774Ivan Stankovic54
尚未招募
Unknown
Evaluating antioxidant and anti-inflammatory effects and safety of rosemary/ginger extracts at different doses in healthy or high-risk subjects
KCT0009408Seoul National University of Science and Technology72