Intravenous Cannulation In Children During Sevoflurane Induction: Which Time is Adequate
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 主要终点
- laryngospasm
研究概览
简要总结
The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2). The aim of the investigator's study is to determine whether one should make iv attempts during the early induction period (at 60seconds) or lately (90 or 120 s) and waiting until the child receives additional sevoflurane inhalation anesthesia
详细描述
the investigators conducted a prospective randomized study, after obtaining Institutional review board approval, which didn't require written parental consent. Children age 1-12 years, undergoing elective general anesthesia via an inhalation induction were randomized to one of three groups of 30 patients each one, for iv placement, either 60s (group E), 90 or 120 s (group L) following loss of lid reflex. Movement on iv placement and incidence of laryngospasm were determined. Difficulty with iv placement was also recorded. Statistical analysis included contingency testing, ANOVA, and non parametric testing. A P-value <0.05 was considered significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 1 Year 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I, II
- •Age from 1 to 12 years old
- •Ambulatory surgery under general anesthesia.
排除标准
- •Age <1 year or> 12 years
- •non-ambulatory surgery,
- •contraindication for induction with sevoflurane
结局指标
主要结局
laryngospasm
时间窗: Time From Intravenous Cannulation to patient extubation
The incidence of laryngospasm
Movement on iv placement
时间窗: In the first 5 min after the anesthesic induction with sevoflurane
Number of children who presented movement on iv placement
次要结局
未报告次要终点
研究者
Ben ALI Manel
Clinical Professor
University Hospital Fattouma Bourguiba