The Methylation Regulation Mechanism of Blood Stasis Relevant miRNA Expression on Coronary Heart Disease
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- major adverse cardiovascular events
研究概览
简要总结
In this study, typical cases of coronary heart disease are selected. They will be intervened by Xuesaitong soft capsules to investigate efficacy and safety for Coronary Heart disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of coronary angiography unstable angina
- •Clinical diagnosis of unstable angina
- •Age of 30 to 75 years old
- •Not use thrombolysis, dilate coronary drugs within two weeks
- •Sign the consent
排除标准
- •Severe valvular heart disease
- •Insulin-dependent diabetes
- •mental disease
- •Combined with severe liver, kidney, hematopoietic system disorder
- •Patients with malignant tumors
- •Pregnancy or breast-feeding women
- •Recent history of trauma
- •Drug allergy
研究组 & 干预措施
Xuesaitong soft capsule group
Patients who confirmed by coronary angiography and diagnosed blood stasis syndrome of coronary heart disease are given conventional Western medicine treatment and Xuesaitong soft capsule.
干预措施: Xuesaitong soft capsule (Drug)
Placebo Comparator
Patients who confirmed by coronary angiography and diagnosed blood stasis syndrome of coronary heart disease are given conventional Western medicine treatment and placebo.
干预措施: Placebo oral capsule (Drug)
结局指标
主要结局
major adverse cardiovascular events
时间窗: 60 days
death, myocardial infarction, hospitalization for unstable angina or stroke
blood stasis syndrome scale of Coronary heart disease angina pectoris
时间窗: 60
to evaluate patients by blood stasis syndrome scale of Coronary heart disease angina pectoris
Seattle Angina Questionnaire
时间窗: 60 days
to evaluate patients by Seattle Angina Questionnaire
次要结局
- lipid(60)
研究者
Jie Wang
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Guang'anmen Hospital of China Academy of Chinese Medical Sciences