EFFICACY AND SAFETY OF PRE-EMPTIVE USE OF ORAL TAPENTADOL VERSUS ORAL PREGABALIN FOR POST OPERATIVE ANALGESIA FOLLOWING CARDIAC SURGERY: A COMPARATIVE STUDY

Dr RIYA SHAH0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年2月21日

试验速览

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•1.Patients posted for elective cardiac surgery using midline sternotomy incision under general anaesthesia
•2.Both males and females
•3.Age group between 18-65 years,
•4.Patients weighing between 40 kg â?? 85 kg

•1.Patients with persistent nausea or vomiting at the time of randomization
•2.Patients on mono amino oxidase inhibitors, tricyclic antidepressants, serotonin norepinephrine reuptake inhibitors
•3.Patients with Epilepsy, traumatic brain injury, stroke, transient ischemic attack, or brain tumor
•4.Patients with opioid tolerance or opioid dependence
•5.Patients having renal disease (creatinine >1.4 mg/dL)
•6.Patients having liver disease (total bilirubin >1.5 mg/dL)
•7.Patients having known allergies to any of the study drug
•8.Patients having major psychiatric disorder
•9.Pregnancy
•10.Patients with left ventricular dysfunction (ejection fraction < 40%), patients on preoperative vasoactive drugs orintraaortic balloon pump (IABP)

发起方

Dr RIYA SHAH