Magnesium Supplement in Early Pregnancy After ICSI
试验速览
- 阶段
- 3 期
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- 1st trimesteric abortion
研究概览
简要总结
Daily supplement of magnesium after biochemical diagnosis of pregnancy in females pregnant after ICSI and through out 1st trimester
详细描述
a fall of magnesium levels at 2-3 weeks of gestation. This drop of magnesium concentration is larger following IVF as compared to spontaneous pregnancies.
so magnesium supplement start after biochemical diagnosis of pregnancy and throughout the 1st trimester
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age 25_38 years
- •BMI 25_30
- •females pregnant after ICSI after biochemical diagnosis of pregnancy
排除标准
- •females with poor ovarian reserve and poor responders
- •abnormality in uterine cavity detected by hysteroscopic evaluation pre ICSI and not treated
- •hydrosalpinx
研究组 & 干预措施
placebo
90 female pregnant after ICSI after biochemical diagnosis of pregnancy will receive placebo oral tablet
干预措施: Placebo Oral Tablet (Drug)
Magnesium supplement
90 female pregnant after ICSI after biochemical diagnosis of pregnancy will receive 500 mg magnesium supplement
干预措施: Magnesium Oxide (Drug)
结局指标
主要结局
1st trimesteric abortion
时间窗: 13 week of gestation
Either spontaneous or missed abortion
次要结局
未报告次要终点
研究者
Radwa Rasheedy Ali
lecturer
Ain Shams University