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临床试验/NCT01927926
NCT01927926已完成不适用

The Effects of Consuming Between- Meal, High Protein Polydextrose Containing Snack Bars on Subjective Satiety, Energy Intake and Metabolic Responses.

University of Nottingham1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2008年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Energy intake at an ad libitum lunchtime test meal

研究概览

简要总结

Developing functional foods that enhance satiety may be beneficial to individuals to help manage body weight.

We have previously shown that consuming a mid-morning liquid preload with increasing proportion of energy derived from whey protein and addition of polydextrose reduced voluntary energy intake at a lunchtime meal compared to a liquid preload of the same energy content but lower in protein and containing no polydextrose.

This study aims to investigate if these results can be replicated when the preload is in the form of a snack bar. We will also investigate whether the daily consumption of the snack bar has an effect on energy intake, subjective appetite and metabolic parameters compared to a control snack of the same energy but with a minimal protein content and without the addition of polydextrose.

We hypothesize that the whey protein polydextrose snack will reduce voluntary energy intake at a subsequent test meal, suppress subjective appetite ratings compared with the control snack bar.

详细描述

Background:

Developing functional food products that enhance satiety, suppress appetite, and reduce subsequent voluntary food intake to a greater extent than a similar energy matched food product, may be useful to help consumers adhere to energy restricted diets and optimize successful body weight management. A range of foods and food constituents have been reported to have the potential to produce short term changes in appetite and energy intake. However, the effects of consuming foods containing such ingredients on appetite, energy intake over the longer term is unclear.

We have previously shown that consuming a mid-morning liquid preload with increasing proportion of energy derived from whey protein and addition of polydextrose reduced voluntary energy intake at a lunchtime meal compared to a liquid preload of the same energy content but lower in protein and containing no polydextrose.

Aims:

This study aims to investigate if previous findings can be replicated using solid snack bars containing whey protein and polydextrose. We will also investigate whether the daily consumption of the snack bar has an effect on energy intake, subjective appetite and metabolic and endocrine responses.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • BMI 18-25 kg/m2

排除标准

  • BMI <18 > 25 kg/m2
  • Dieting or weight loss
  • Presence of disease (e.g. diabetes, cardiovascular disease, cancer etc)
  • Currently regularly taking medications
  • Restrained eaters (defined as restraint score >7 on TFEQ)

结局指标

主要结局

Energy intake at an ad libitum lunchtime test meal

时间窗: Day 1

Energy intake at a lunchtime test meal served 90 min following the consumption of the snack bar on day 1.

次要结局

  • Energy intake at an ad libitum lunchtime test meal(Day 15)
  • Subjective appetite responses(Day 15)
  • Remainder of the day energy intake(Day 15)
  • Free living energy intake(Day 12)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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