Functional Cereal-based Products Fortified With Legumes for Satiety and Weight Management
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Change in glucose AUC
研究概览
简要总结
Legumes are rich source of proteins and dietary fibers which are associated with satiety and amelioration of postprandial glycemic response. The purpose of the study is to examine the effects of cereal-based products fortified with legumes on appetite regulation and body weight management.
详细描述
Postprandial glycemic response as well as response of hormones related to appetite regulation after consumption of cereal-based products fortified with legumes will be evaluated. Apparently healthy subjects with normal body weight and overweight subjects will participate in the study (two protocols). Certain effects on metabolites related to the composition of the different products will be examined. The results of the study will help in the design of a long-term clinical trial regarding the effects of the functional products on body weight management in overweight subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
盲法说明
Foods do not differ in shape or color. Participants are blinded to the treatments.
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •normal exercise and dietary habits
- •weight stable for at least 3 months before enrollment
排除标准
- •pregnancy
- •chronic medical illness
- •use of nutritional supplements
- •regular intense exercise
- •alcohol consumption >2 drinks per day
结局指标
主要结局
Change in glucose AUC
时间窗: Time points: 0 (before food consumption), 30, 60, 90,120,180 minutes postprandially for each food (totally four times)
Change in glucose AUC after consumption of the products compared to the AUC after consumption of the reference food
次要结局
未报告次要终点
研究者
Amalia Yanni
Research and Teaching Associate-Staff
Harokopio University