Addition of Popliteal Plexus Block to Continuous Femoral Nerve Block for Total Knee Arthroplasty
试验速览
- 阶段
- 不适用
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Total iv morphine consumption (mg)
研究概览
简要总结
The popliteal plexus block has been described as an alternative analgesic postoperative pain treatment for total knee arthroplasty. It consists of injecting local anaeshetics inside the distal end of the adductor canal close to the adductor hiatus, adjacent to the femoral artery, between the medial vastus muscle and the adductor magnus muscle, in order to anesthetize the popliteal plexus. However, the analgesic efficacy has never been demonstrated in a randomized controlled trial. Therefore the objective of this study is to investigate the analgesic benefit of this block combined with a continuous femoral nerve block, on patients scheduled for total knee athroplasty.
详细描述
Patients scheduled to undergo total knee arthroplasty under general anesthesia will be randomly allocated to two groups: continuous femoral nerve block alone or continuous femoral nerve block with addition of a popliteal plexus block.
The continuous femoral nerve block will be performed by the anesthesiologist with 15 mLs of ropivacaine 0.5%, under ultrasound guidance before the beginning of the general anesthesia. The popliteal plexus block will be done by the anesthesiology, under ultrasound guidance, before the beginning of the surgery, under general anesthesia.
Postoperative analgesia will include acetaminophen (4 x 1000 mg), ibuprofen (3 x 400 mg) and a continuous infusion of Ropivacaine 0.2%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients scheduled for total knee athroplasty under general anesthesia
排除标准
- •Kidney disease with GFR < 50 ml/mn
- •Daily opioid consumption > 1 month
- •Allergy to local anesthetics
- •Neurological problems of the lower extremity
- •other contraindications to peripheral nerve blocks
研究组 & 干预措施
Popliteal plexus block and continuous femoral nerve block
干预措施: Ropivacaine 0.5% Injectable Solution (Drug)
continuous femoral nerve block
干预措施: Ropivacaine 0.5% Injectable Solution (Drug)
结局指标
主要结局
Total iv morphine consumption (mg)
时间窗: 12 postoperative hours
次要结局
- Average and maximum pain scores (Numeric rating scale 0-10)(12, 24 and 48 postoperative hours)
- Popliteal plexus block duration of action (hours)(up to 48 postoperative hours)
- Knee pain localization (anterior, internal, posterior, lateral, medial)(2, 12, 24 and 48 postoperative hours)
- Popliteal plexus block procedure time (minutes)(When performing the popliteal plexus block)
- Total iv morphine consumption (mg)(24 and 48 postoperative hours)
- Plantarflexion and dorsiflexion ankle strength (Newtons)(2 and 24 postoperative hours)
- Sciatic extension of popliteal plexus block(2 and 24 postoperative hours)
研究者
Kevin Stebler
Principal Investigator
University Hospital, Geneva