Epidemiological and Therapeutic Characterization Study of Psoriatic Disease in Patients Under 18 Years of Age at the Costa Rican Social Security (2018-2025)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Treatment patterns used in pediatric psoriasis in real-world clinical practice (topical, phototherapy, systemic, biologic).
研究概览
简要总结
The goal of this retrospective observational study is to characterize the clinical features, severity, comorbidities, and treatment patterns of pediatric psoriasis in patients managed in the Costa Rican Social Security System. The main questions it aims to answer are:
What are the demographic and clinical characteristics of pediatric psoriasis in Costa Rica?
What disease severity profiles, comorbidities, and treatments are observed in routine care?
All patients <18 years with confirmed psoriasis evaluated during the study period will be included. Data will be obtained from electronic health records without intervention or modification of treatment.
详细描述
Pediatric psoriasis is a chronic immune-mediated inflammatory dermatosis associated with physical, psychosocial, and metabolic comorbidity burden beginning early in life. Epidemiologic and clinical data in Latin American pediatric populations remain limited, particularly in real-world care settings. This study is a retrospective observational characterization of pediatric psoriasis patients managed in the Costa Rican Social Security System. Unlike interventional trials or biologic-specific registries, it analyzes existing clinical records to describe demographic distribution, clinical subtypes, severity (PASI/BSA/DLQI or pediatric indices), comorbidities, and treatment patterns in routine practice. No therapeutic interventions or standardized follow-up are introduced. By capturing real-world pediatric psoriasis presentation and management in Costa Rica, the study provides baseline national evidence distinct from drug-specific or prospective therapeutic studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients younger than 18 years at the time of psoriasis diagnosis.
- •Clinical diagnosis of psoriasis established by a specialist physician (dermatologist or trained pediatrician) or by a general practitioner within the Costa Rican Social Security System (CCSS).
- •Patients evaluated in CCSS healthcare facilities between January 2018 and December
- •Clinical records containing sufficient information on key epidemiologic and therapeutic variables relevant to the study (age, sex, date of diagnosis, clinical subtype, and treatment received).
排除标准
- •Patients aged 18 years or older at the time of psoriasis diagnosis.
- •Clinical records incomplete or lacking sufficient information for analysis of the main study variables.
- •Patients with uncertain or unconfirmed diagnosis of psoriasis.
结局指标
主要结局
Treatment patterns used in pediatric psoriasis in real-world clinical practice (topical, phototherapy, systemic, biologic).
时间窗: January 2018- December 2025
Clinical and severity characteristics of pediatric psoriasis, including subtype and severity indices (e.g., PASI/BSA/DLQI or pediatric-adapted measures) documented in routine care.
时间窗: January 2018- December 2025
Comorbidity profile in pediatric psoriasis (e.g., metabolic, cardiovascular risk factors, psoriatic arthritis).
时间窗: January 2018- December 2025
次要结局
未报告次要终点
研究者
Daniel Barquero Orias
Sub-Investigator
Caja Costarricense de Seguro Social