A comparative study of the effect of inhalational anaesthetic agents: Sevoflurane, Isoflurane and Desflurane on the blood glucose levels in non diabetic patients under general anaesthesia

All India Institute of Medical Sciences Raipur1 个研究点分布在 1 个国家目标入组 105 人开始时间: 2021年12月15日最近更新: 2023年3月26日

试验速览

阶段: 不适用
状态: 已完成
发起方: All India Institute of Medical Sciences Raipur
入组人数: 105
试验地点: 1
主要终点: Blood glucose levels

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The study will be conducted to observe the effects of Sevoflurane, Isoflurane and Desflurane on blood glucose levels in non-diabetic patients. Very few research articles are available on this study and hence the results obtained from this study will be useful in choosing the appropriate inhalational agent in patients and can help in achieving better glycemic control.The results obtained will also be a useful research tool for further studies in diabetic patients.

研究设计

研究类型: Interventional
分配方式: Coin toss, Lottery, toss of dice, shuffling cards etc
盲法: Not Applicable

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）

入选标准

•1.Age: 18 to 60 years 2.Gender: both male and female 3.ASA grade: I or II 4.Duration of surgery : Minimum 2 hours.

排除标准

•1.Patient refusal 2.Diabetic patient/ hyperglycemic patient 3.Hypertensive patient 4.Patient on drugs causing hypo or hyperglycemia like steroids, OHA, etc.
•5.Contraindication to inhalational anesthetic agents- Uncontrolled hypotension, previous history of malignant hyperthermia, increased intracranial pressure 6.Patient requiring Rapid sequence intubation 7.Patients with pancreatic disorders such as chronic pancreatitis, carcinoma pancreas, etc 8.Patients with Catecholamine secreting tumors 9.Patients undergoing pancreatic surgeries.

结局指标

主要结局

Blood glucose levels

时间窗: baseline, preinduction, at MAC 1, at 15 minute intervals intraoperatively, AFter achieving MAC 0, Postoperative

次要结局

Best inhalational agent with respect to glycemic control(Blood glucose at baseline, preinduction, at MAC 1, at 15 minute intervals intraoperatively, AFter achieving MAC 0, Postoperative)

研究者

发起方

All India Institute of Medical Sciences Raipur

申办方类型

Research institution and hospital

研究点 (1)

Loading locations...

相似试验

Unknown

4 期

Pulmonary Mechanics During Minimally Invasive Repair of Pectus ExcavatumPectus Excavatum

NCT01486953The Catholic University of Korea70

Unknown

不适用

Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function TestsPituitary Adenoma

NCT02709863Istanbul University90

已完成

不适用

Desflurane in Children With Laryngeal Mask AirwayDesflurane Anesthesia

NCT02470442Seoul National University Hospital200

尚未招募

不适用

Effects of two inhalation anesthetics (sevoflurane, desflurane) on ventilatory impairment induced by remifentanil; retrospective studyElderly patients undergoing femur fracture surgery under general anesthesia

JPRN-UMIN000045343agano municipal hospital Division of anesthesia300

招募中

4 期

Inhalation anesthesia with sevoflurane vs intravenous anesthesia with propofol and dexmedetomidine on postoperative nausea vomiting and recovery parameters after anesthesia

CTRI/2023/08/057104Apollo Hospitals Bilaspur