跳至主要内容
临床试验/NCT03750721
NCT03750721已完成不适用

Staphylococcal Acute Post-Operative Prosthetic Joint Infection Treated With 'DAIR' (Debridement and Implant Retention) And Impact Of Rifampin: A Retrospective Cohort Study In France

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 79 人开始时间: 2018年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
79
试验地点
1
主要终点
description of the use of rifampicin : rate of use

研究概览

简要总结

S. aureus and coagulase-negative staphylococci are the most frequent bacteria responsible for PJI (prosthetic joint infection). The aim of this study is to describe the use of rifampicin.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients having had acute PJI (i.e. <1 month following the implantation), DAIR with exchange of removal components) due to S. aureus and coagulase-negative staphylococci (2011-2016)

排除标准

  • 未提供

结局指标

主要结局

description of the use of rifampicin : rate of use

时间窗: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption)

the aim is to determine how the use of rifampin influence the prognosis in staphylococcal acute post-operative prosthetic joint infection treated with DAIR

次要结局

  • rate of failure for treatment using rifampin(Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption))
  • rate of adverse event with rifampin(Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Eugénie MABRUT

Clinical Research Assistant

Hospices Civils de Lyon

研究点 (1)

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