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临床试验/CTRI/2022/05/042829
CTRI/2022/05/042829已完成不适用

Comparison of erector spinae plane block and local anaesthetic infiltration of the incision site with 0.375% ropivacaine for postoperative analgesia in percutaneous nephrolithotomy.

velammal medical college1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年1月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
100
试验地点
1
主要终点
Postoperative Numeric rating pain scale

研究概览

简要总结

Erector spinae block is found to be effective in variety of procedures.This study is designed to evaluate the efficacy of USG guided Erector spinae block(ESP) for postoperative analgesia following percutaneous nephrolithotomy(pcnl).It is a prospective double blind parallel group study comparing erecor spinae block with local site infiltration with 0.375% ropivacaine for postoperative pain relief for pcnl.Inclusion criteria included ASA 1 and 2 patients aged between 18 and 70 years  of both sexes.Exclusion criteria included BMI>35 KG/m2 ,ASA 3 AND 4,allergic history to local anaesthetics,sepsis or bacreimia.Patients in group L received 20ml of 0.375% ropivacaine at the incision site subcutaneously with hupodermic needle locally and Group E received USG guided ESP block with 0.375% ropivacaine at T10 level.Numeric rating pain scale was measured postoperatively at 30 min,60 min then hourly for 6 hours followed by 4th hourly for 24 hours.The primary objective of the study was to compare NRS scores postoperatively between two groups.The secondary objective was to compare the rescue analgesia requirement between both gropus for 24 hours.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • •Inclusion criteria.
  • •Patients undergoing PCNL under general anaesthesia (GA) of both genders belonging to ASA I and II, between 18 to 70 years of age, were included.

排除标准

  • •Exclusion criteria – ASA – III , IV contraindications to peripheral nerve blocks, body mass index >35 kg/m2, sepsis or bacteraemia, and cognitive disability.

结局指标

主要结局

Postoperative Numeric rating pain scale

时间窗: Postoperative Numeric rating scale 0 to 10 measured over 24 hours post procedure

次要结局

  • Postoperative analgesic requirement(time for first rescue analgesia and total analgesic dose required postoperatively)

研究者

发起方
velammal medical college
申办方类型
Research institution and hospital

研究点 (1)

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