An Update on Intracerebral Hemorrhage - A Cohort Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- hematoma volume growth at 24 hours
研究概览
简要总结
The intracerebral hemorrhage study is a multicenter , combination of prospective and retrospective observational cohort study led by Dr. Muhammad Junaid Akram, PhD scholar at Chongqing Medical University. Prof Dr. Qi Li will be the senior consultant for the study. The study will be focusing on natural history, epidemiological , radiological, rehabilitative and clinical aspects as well as the effect of various treatments on the hemorrhagic patients.
The study related data of the patients diagnosed with intracerebral hemorrhage will be collected in prospective and retrospective ways. The prognostic data for the patients will be assembled and collected via using different outcome measures at different points of time.
详细描述
The study will be used to address the several key issues related to intracerebral hemorrhage. The demographics, scores based upon disease severity , mRS, GCS, NIHSS scores will be recorded at baseline and in the prospective and retrospective ways. The data obtained from the registered patients will be used for future use , critical review by expert neurologists, neurorehabilitative experts for further use and review.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years Patients willing to participate via signing a consent form' Patients diagnosed with CT-Confirmed spontaneous intracerebral hemorrhage (ICH) Patients willing to participate in the follow up assessment
排除标准
- •Not willing to participate Secondary ICH to hemorrhagic infarction or tumor bleeding etc. Traumatic ICH
结局指标
主要结局
hematoma volume growth at 24 hours
时间窗: 24 hours
To assess early hematoma volume growth at 24 hours
次要结局
- Perihematomal edema volume measurement at 24 hours(24 hours)
- Perihematomal edema volume measurement at 48 hours(48 hours)
- Perihematomal edema volume measurement at 72 hours(72 hours)
- Major thrombotic events(2 weeks)
- Functional outcome at 3 months assessed by modified Rankin Scale(3 months)
- Early neurological deterioration assessed by NIHSS score at 24 hours(24 hours)
- Early neurological deterioration assessed by NIHSS score at 48 hours(48 hours)
- Intraventricular hemorrhage growth(24 hours)
- Early neurological deterioration assessed by NIHSS score at 72 hours(72 hours)
研究者
Dr. Muhammad Junaid Akram
Dr. Muhammad Junaid Akram
Shifa Clinical Research Center