Chongqing Intracerebral Hemorrhage Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- hematoma volume growth at 24 hours
研究概览
简要总结
The Chongqing intracerebral hemorrhage study is a multi-center, prospective, observational study led by professor Qi Li from Chongqing Medical University. Professor Peng Xie will be the senior consultant for the study. The Chongqing intracerebral hemorrhage study will focus on the epidemiology, natural history, pathogenesis, laboratory, radiological aspects, clinical outcomes and the effects of treatment in patients with intracerebral hemorrhage.
The clinical, laboratory, imaging, genetic and outcome data of patients diagnosed with acute intracerebral hemorrhage will be prospectively collected. The prognosis of patients with intracerebral hemorrhage will be assessed by using several outcome measure scales at different time points.
详细描述
The Chongqing intracerebral hemorrhage study will try to address several key issues in ICH. The baseline clinical data including demographic, disease severity scores, prior drug history and relevant medical history, premorbid mRS scores will be prospectively recorded. The admission and follow-up imaging data of all registered patients will be saved as Dicom format for future use and review. The functional outcomes will be assessed and recorded by experienced neurologists.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >= 18 years
- •Informed consent to participate in the study
- •Patients diagnosed with CT-confirmed spontaneous Intracerebral Hemorrhage (ICH)
- •Patients are willing to participate in the follow up assessment
排除标准
- •Did not agree to participate in the study
- •Secondary ICH to hemorrhagic infarction or tumor bleeding etc.
- •Traumatic ICH
结局指标
主要结局
hematoma volume growth at 24 hours
时间窗: 24 hours
To assess early hematoma volume growth at 24 hours
次要结局
- functional outcome at 3 months assessed by modified Ranking Scale(3 months)
- early neurological deterioration assessed by NIHSS at 48 hours(48 hours)
- early neurological deterioration assessed by NIHSS score(72hours)
- perihematoma edema volume measurement at 24 hours(24 hours)
- perihematoma edema volume measurement at 72 hours(72 hours)
- intraventricular hemorrhage growth(24 hours)
- major thromboembolic events(2 weeks)
- early neurological deterioration assessed by NIHSS score at 24 hours(24 hours)
研究者
Qi Li
Professor
First Affiliated Hospital of Chongqing Medical University