Comparıson Of PENG Block wıth Intra-articular And Quadratus Lumborum Block İn Primary Total Hip Arthroplasty: : Randomized Controlled Double Blinded Trial Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 89
- 试验地点
- 2
- 主要终点
- Numerical Rating Scale (NRS) scores
研究概览
简要总结
90 patients ASA I-III, undergoing Total hip arthroplasty (THA) under spinal anesthesia, will be randomly assigned into one of three groups, namely group A (n=30), where an PENG block, group B (N:30) where an inra-articuler, and group C (n=30) where Quadratus lumborum block will be performed preoperatively. All patients will receive a standardized postoperative analgesia regimen. NRS scores will be evaluated in static and dynamic conditions during the first 48 hours postoperatively.
详细描述
Total hip arthroplasty (THA) is the second most common joint replacement surgery, partly due to the aging population. The primary aim of this study is to compare the analgesic efficacy of Pericapsular nerve group (PENG) block with intra-articular and Quadrotus lumborum block (QLB). Regional anesthesia (RA), such as the recently described pericapsular nerve group (PENG) block, may provide additional analgesic benefit in this situation. Pericapsular nerve group (PENG) block is a new regional anesthesia technique to provide analgesia after hip fractures and hip arthroplasty. The aim of this single-center, double-blind, randomized controlled trial is to confirm the efficacy of PENG block for postoperative recovery after primary THA.
Routine multimodal analgesia will be used for postoperative analgesia
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Physical status according to American Society of Anesthesiologists (ASA ) I-III
排除标准
- •Previous operation on the same hip
- •Hepatic or renal insufficiency
- •Younger than 18 years old and older than 85
- •Patients undergoing general anesthesia
- •Allergy or intolerance to one of the study medications
- •Chronic gabapentin/pregabalin use ( regular use for longer than 3 months)
- •Chronic opioid use ( taking opioids for longer than 3 months, or daily oral morphine equivalent of >5 mg/day one month
结局指标
主要结局
Numerical Rating Scale (NRS) scores
时间窗: 48 Hours
Range 0-10, 0=no pain, 10=the worse pain ever
次要结局
- Opioid consumption(3-6-8-12-24 and 48 hours)
- Patient satisfaction(48 hours)
- Presence of quadriceps motor block (defined as paralysis or paresis )(3-6-12-24 hours after the block)
- Mobilization time(24 hour)
- Static and dynamic pain(3-6-8-12-24 and 48 hours)
- Hip adduction strength(3-6-12-24 hours after the block)
- Presence of postoperative nausea, vomiting, pruritus, urinary retention, respiratory depression(3-6-12-24 hours after the block)
- Quality of Recovery (QoR-40) score(measurements are obtained at 24 hours, 48 hours, and one week)