跳至主要内容
临床试验/NCT07523659
NCT07523659招募中不适用

The Influence of Climate and Air Pollution on Physical Activity of Chinese People in Shenyang(41.481175ºN) and Shenzhen(22.324386ºN)

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences2 个研究点 分布在 1 个国家目标入组 124 人开始时间: 2024年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
124
试验地点
2
主要终点
Physical activity level

研究概览

简要总结

Physical activity (PA) refers to bodily movements that result in a significant increase in energy expenditure due to the contraction of skeletal muscles. Physical inactivity has become a major global public health concern and is currently the fourth leading cause of death worldwide. The World Health Organization (WHO) recommends that adults engage in at least 150 minutes of moderate-intensity physical activity (MPA) or 75 minutes of vigorous-intensity physical activity (VPA) per week.

Although some studies suggest that individual differences in PA may have a genetic basis, PA is generally considered to be largely under voluntary control and influenced by climatic and environmental factors. For instance, extreme temperatures-either hot or cold-can increase health risks and reduce individuals' willingness to engage in physical activity. In addition, air pollution, particularly fine particulate matter (PM2.5), poses serious health risks. Exercising in polluted environments may trigger asthma, cardiovascular, or pulmonary conditions.

Since the Industrial Revolution, fossil fuel emissions have contributed to a global surface temperature increase of approximately 1.1°C, with projections suggesting a further rise of 2.5-2.9°C by the end of the century. At the same time, PM2.5 pollution has become a pressing issue, contributing to an estimated 7 million deaths globally in 2012-over one-third of which occurred in rapidly developing Asian countries.

Given the seasonal and geographic variability in climate and air quality, physical activity levels are likely to be affected accordingly.This study aims to investigate the extent to which climatic and environmental factors influence physical activity levels and intensity.

详细描述

This study will be conducted in two cities in China: Shenyang (41.481175°N) and Shenzhen (22.324386°N), with 62 participants recruited from each location. By assessing participants' body composition and physical activity levels, along with the climatic and environmental conditions in both cities, we aim to compare how different climates and environmental exposures influence physical activity.

Participants will be asked to wear a GT3X accelerometer every two months to monitor physical activity levels, and an iButton temperature sensor to record ambient temperature. A total of six measurement rounds will be conducted. Concurrently, atmospheric temperature data will be collected via local weather stations, and PM2.5 data will be obtained from publicly available sources.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18 to 55 years
  • Residing in Shenzhen or Shenyang for the entire year

排除标准

  • Disabilities that limit physical activity
  • Any condition preventing participation in physical activity
  • Pregnant or planning pregnancy during the study period
  • Lactating or planning to lactate during the study period

研究组 & 干预措施

Subjects in Shenzhen

The investigators planned to recruit 62 subjects in Shenzhen. Shenzhen is located in 22.324386ºN, 114.031040ºE, the south of China, with long summers and short winters, high temperatures and frequent rains. The average annual temperature is 23.3℃. In addition, Shenzhen is a city with good economic and technological development. The investigators will measure the physical activity of subjects, and the Temperature, humidity and PM2.5 data of Shenzhen.

Subjects in Shenyang

The investigators planned to recruit 62 subjects in Shenyang. Shenyang is located in 41.481175ºN, 123.253118ºE, the northeastern of China, with cold winters and warm summers, also has long cold periods. The average annual temperature ranges from 6.2 to 9.7℃. In addition, Shenyang focuses on industrial development. The investigators will measure the physical activity of subjects, and the Temperature, humidity and PM2.5 data of Shenyang.

结局指标

主要结局

Physical activity level

时间窗: Through study completion, every two months across 6 assessment rounds, up to 12 months per participant

Physical activity in vector magnitude counts will be recorded using GT3X accelerometer worn near the hip for a consecutive period of 7 days. The monitor should not be worn while bathing or swimming.

次要结局

  • Temperature(Through study completion, an average of 2 years)
  • Humidity(Through study completion, an average of 2 years)
  • Subject exposure to environmental temperature(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)
  • PM2.5(Through study completion, an average of 2 years)
  • Sunshine duration(Through study completion, an average of 2 years)
  • Height(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)
  • Body Weight(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)
  • Fat percentage(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)
  • Fat mass(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)
  • Fat-free mass(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)
  • Muscle mass(Through study completion, every two months across 6 assessment rounds, up to 12 months per participant)

研究者

发起方
Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
申办方类型
Other
责任方
Principal Investigator
主要研究者

John R. Speakman

Professer

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

研究点 (2)

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