CTRI/2019/06/019501尚未招募2 期
ESCALATE: Linezolid As An Add On Treatment In The Intensive Phase Of Tubercular Meningitis-A Randomised Controlled Trial - ESCALATE
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- Aiims
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age 18 years old or older
- •2.Willing to participate in the study by signing informed consent
- •3.Clinically diagnosed as TB meningitis by standard criteria using clinical, CSF and radiological findings
排除标准
- •1.Failure to perform lumbar puncture
- •2.HIV positivity
- •3.Disseminated tuberculosis
- •4.Proven MDR, XDR TB
- •5.Confirmed meningitis other than TB
- •6.On tubercular drug for more than 15 days
- •7.Current treatment with: MAO inhibitors, direct and indirect acting sympathomimetic drugs
- •8.Pregnant or lactating female
- •9.Hepatic insufficiency (ALT >5x upper normal limit)
- •10.Kidney dysfunction (eGFR <50ml/min)
- •11.Known hypersensitivity to rifampicin and/or linezolid
研究者
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