ACTRN12622000908730进行中（未招募）未知
Efficacy and neural mechanisms of computerised cognitive training in Huntington’s disease: A randomised controlled trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Inclusion criteria include:
- •(a) Genetically positive for Huntington’s disease (HD)
- •(b) Premanifest disease or early-stage manifest disease (total functional capacity [TFC] = 7-13)
- •(c) 18+ years of age
- •(d) Access to computer with Internet connection
排除标准
- •Exclusion criteria include:
- •(a) Absence of known genetic confirmation for HD
- •(b) Late-stage disease (TFC < 7)
- •(c) Under 18 years of age
- •(d) Diagnosis of any major neurological or psychiatric condition other than HD (besides anxiety or depression), history of substance abuse or head injury
- •(e) Severe depression and anxiety symptoms (score > 14 on either HADS subscale)
- •(f) Unstable dose of medication for depression and anxiety in the last 6 months
- •Additional exclusion criteria if undergoing MRI:
- •(a) Left-handed
- •(b) Currently pregnant
- •(c) Other MRI contraindications
研究者
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