NCT02806388招募中不适用
Individualized Molecular Profiling for Allocation to Clinical Trials (IMPACT) Project
National Cancer Centre, Singapore1 个研究点 分布在 1 个国家目标入组 5,500 人开始时间: 2011年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 5,500
- 试验地点
- 1
- 主要终点
- The molecular and clinical epidemiology for cancer patients being considered for novel therapeutics
研究概览
简要总结
This study aims to screen tumor molecular profile for better selection of anticancer treatment, in particular, allocation to clinical trials if available.
详细描述
Molecular profiling will be performed on archival tumor tissue or freshly collected tumor tissue from re-biopsy. Blood, pleural fluid, FNA, and/or saliva may be collected to study the genetic makeup and also to compare the tumor molecular profile. Personalized therapy will be given based on molecular profile.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 12 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed histological diagnosis of solid tumor
- •Suitable for systematic treatment and clinical trials
- •ECOG (Eastern cooperative oncology group) performance status < 2
- •Able to provide tumor tissue for molecular profiling
- •Able to understand and sign the informed consent form
排除标准
- 未提供
结局指标
主要结局
The molecular and clinical epidemiology for cancer patients being considered for novel therapeutics
时间窗: 5 years
次要结局
- The correlation of molecular profiles with clinical outcomes(5 years)
- The proportion of patients who have actionable alterations and enrol into clinical trials(5 years)
研究者
研究点 (1)
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