Trial of Provider Notification for Patients With High B-type Natriuretic Peptide and no Imaging to Identify Unsuspected Heart Failure.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 115
- 试验地点
- 2
- 主要终点
- Measurement of left ventricular ejection fraction
研究概览
简要总结
This proposal examines use of a clinical reminder to the primary provider of patient with a high B type natriuretic peptide but no prior imaging.
Electrical Medical Record-based Intervention to Determine whether Clinical Reminders Improve Heart Failure Management in Patients with High BNP Values and Unknown LVEF.
详细描述
Rationale: B type natriuretic peptide is known to be elevated (> 100 pg/ml) in patients with heart failure. Furthermore, treatments are available to improve survival and reduce hospitalization if the left ventricular ejection fraction (LVEF) is < 40%. Accordingly, guidelines recommend an LVEF measure for patients with suspected heart failure. Prior work has demonstrated that patients with high BNP values do not always have a measure of left ventricular ejection.
Hypothesis
A reminder to patients with BNP and no imaging may prompt providers to order appropriate imaging potentially leading to 1) identification of unsuspected depressed ejection fraction and 2) more appropriate treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BNP >= 200 pg/ml in last 2 months
排除标准
- •Measure of LVEF in the last 12 months
- •Last measure of LVEF < 40%
结局指标
主要结局
Measurement of left ventricular ejection fraction
时间窗: 6 months after randomization
numerator: Measurement of left ventricular ejection fraction within 6 months of randomization. denominator: All randomized patients
次要结局
- Treatment of Low LVEF(6 months following randomization)
- Identification of LVEF < 40%(6 months following randomizaiton)
研究者
Paul Heidenreich
Investigator
VA Palo Alto Health Care System