Effects of High-intensity Interval Training Combined With Post-exercise Protein Supplementation on Cardiorespiratory Fitness in Untrained Individuals: a Double-blind Placebo-controlled Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Cardiorespiratory Fitness (CRF)
研究概览
简要总结
The aim of this study is to investigate the effects of an 8-week high-intensity interval training (HIIT) or HIIT plus resistance training program combined with post-exercise protein supplementation on cardiorespiratory fitness and cardiometabolic risk indices in previously untrained individuals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Randomized, double-blind placebo-controlled study. Participants and Outcome Assessors will not be aware of the arm to which the participants are allocated (double-blinded masking).
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Sedentary Lifestyle over at least 6 months prior to the study
排除标准
- •Pregnancy, Lactation
- •Psychological disorders, epilepsy, sever neurological disorders
- •Participation in other exercise- or nutrition studies within the last 6 months
- •coronary heart disease, heart failure
- •malignant disease
- •severe rheumatic or neurological disease
- •severe/unstable hypertension (resting RR: >180/>110 mmHg)
- •severely restricted lung function (FEV1 <60%)
- •unstable Diabetes mellitus
- •severe orthopedic disease/restriction
- •acute / chronic infectious diseases
- •Electronic implants (defibrillator, pacemaker)
- •Persons in mental hospitals by order of authorities or jurisdiction
结局指标
主要结局
Cardiorespiratory Fitness (CRF)
时间窗: 8 weeks
CRF will be assessed by measuring maximum oxygen uptake (VO2max)
Muscle strength (only in groups with resistance training)
时间窗: 8 weeks
Maximum strength (Fmax) of the major muscle groups (chest, upper back, lower back, abdominals and legs) will be estimated through submaximal tests, based on the performance of multiple repetitions.
次要结局
- Health-related quality of life(8 weeks)
- Cardiometabolic Risk Score (MetS-Z-Score)(8 weeks)
- Fat mass(8 weeks)
- Muscle mass(8 weeks)
- Insulin sensitivity(8 weeks)
- Inflammation status(8 weeks)