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临床试验/NCT06438211
NCT06438211已完成不适用

Comparison of Postoperative Analgesic Effectiveness of Superficial and Deep Serratus Plane Blocks in Patients Undergoing Mastectomy

TC Erciyes University2 个研究点 分布在 2 个国家目标入组 63 人开始时间: 2024年6月24日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
63
试验地点
2
主要终点
postoperative morphine consumption

研究概览

简要总结

Pain after breast surgery can be quite severe and can significantly affect quality of life. By successfully treating acute pain, it is aimed to prevent the formation of pain memory and to ensure that chronic pain never occurs. It is known that by using regional techniques, the use of general anesthetics and opioids can be reduced and their harmful effects can be limited. In this study, it will be compared the analgesic effectiveness of superficial and deep serratus plane blocks in the postoperative acute and chronic periods.

详细描述

Acute and chronic pain is a serious problem in patients undergoing breast surgery. Apart from the feeling of pain, it also causes psychological difficulties, increased hospital stays, delays or difficulties in mobilization, and so on. Due to all these reasons, postoperative pain control is very important.

Although opioids are the gold standard in the treatment of pain, their side effect profiles (sedation, respiratory depression, constipation, tolerance development, etc.) limit their use and different searches are on the agenda. There are studies showing that superficial and deep serratus plane blocks are effective in mastectomy operations. In this study, patients who underwent mastectomy these two blocks will be compared to see which one is superior and to investigate the differences that may occur in the acute and chronic periods.

After general anesthesia induction, a superficial serratus plane block will be performed on the first group of patients undergoing surgery by applying local anesthetic to the fascia between the serratus anterior and latissimus dorsi muscles at the level of the 4th and 5th ribs under ultrasound. then the patient will undergo surgical procedure. Likewise, for the second group of patients, after general anesthesia induction, a deep serratus plane block will be performed by applying local anesthetic between the rib and the serratus anterior muscle at the level of the 4th and 5th ribs, under ultrasound guidance, and the patient will be taken into surgery. Both groups of patients will be monitored for 24 hours after the operation with a patient-controlled analgesia device. Patients' pain scores, satisfaction scores, nausea and vomiting scores, and additional analgesic needs will be recorded 24 hours postoperatively.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • patients who will undergo mastectomy surgery
  • patients who agreed to participate in the study
  • ASA I-II patients

排除标准

  • Patients planned for bilateral breast surgery
  • Patients who have had previous breast surgery
  • Patients with existing neuropathic pain or receiving treatment for neuropathic pain
  • Patients with psychiatric disorders
  • Patients with opioid addiction
  • Patients allergic to local anesthetics

结局指标

主要结局

postoperative morphine consumption

时间窗: 24 hours

How much morphine the patient consumed in the first 24 hours postoperatively with a patient-controlled anesthesia device

次要结局

  • measuring pain scors(24 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ayse Ulgey

Professor doctor

TC Erciyes University

研究点 (2)

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