Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 181
- 试验地点
- 10
- 主要终点
- Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 3 Months
研究概览
简要总结
This study will examine the effects of a first-line treatment for major depressive disorder (MDD), interpersonal psychotherapy (IPT), among men and women prisoners.
详细描述
The purpose of this 3-year randomized trial is to promote uptake of evidence-based treatment in criminal justice settings by conducting a fully-powered randomized effectiveness study that collects pilot implementation data, including cost-effectiveness data. Group IPT will be compared to treatment as usual (TAU) in a sample of 90 male and 90 female prisoners with MDD from 4 institutions, allowing us to explore gender effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meet all DSM-IV criteria for primary (non-substance induced) major depressive disorder
- •Expectation of at least 6 months of incarceration at baseline interview
- •Incarcerated for at least 4 weeks
排除标准
- •Lifetime:
- •Bipolar disorder
- •Psychotic disorder
- •Are imminently suicidal
- •Cannot understand English well enough to understand the consent form or assessment instruments when read aloud
结局指标
主要结局
Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 3 Months
时间窗: 3 Months from Baseline
次要结局
- Change from Baseline in Suicidality at 6 Months(6 Months from Baseline)
- Cost-effectiveness(6 months post-baseline)
- Change from Baseline in Hamilton Rating Scale for Depression (HRSD) at 6 Months(6 Months from Baseline)
- Change from Baseline in Suicidality at 3 Months(3 Months from Baseline)
- Change from Baseline in In-Prison Functioning at 3 Months(3 Months from Baseline)
- Change from Baseline in In-Prison Functioning at 6 Months(6 Months from Baseline)
研究者
Dr. Jennifer Johnson
Associate Professor (Research), Department of Psychiatry and Human Behavior
Brown University