NL-OMON43075尚未招募不适用
The role of perivascular adipose tissue in the regulation of insulin sensitivity through muscle microvascular recruitment in individuals with obesity or type 2 diabetes before and after bariatric surgery. - PVAT, metabolism and vascular health.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •Female -Caucasian -age 18-55 years -BMI is *35 kg/m2
- •Bariatric surgery participants getting an operation at the OLVG, location West. Control participants getting a cholecystectomy at the OLVG west.
排除标准
- •Documented CVD -Stage 2 hypertension (resting blood pressure >160/100 mmHg) -Obstructive sleeping apnea syndrome (OSAS). -History of severe inflammatory conditions in the past 15 years -Recent infections -recent history (<12 months) of high alcohol use > 4 U/day, more than 3 days in a row -Use of medication potentially affection insulin sensitivity, microvascular function or inflammation -Use of anticoagulants (types Warfarin and Coumadin derivatives) that can increase the risk of bleeding during the muscle biopsy (exception is made for aspirin). -Malignancies (except those of the skin), renal and hepatic diseases. -Smoking -Recent (<6 months) marked (>10%) changes in body weight.
研究者
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