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临床试验/CTRI/2024/08/072682
CTRI/2024/08/072682尚未招募2 期

Comparative evaluation of locally delivered moringa oleifera gel and chlorhexidine gel as an adjunct to scaling and root planing in generalized periodontitis patients - A randomised cotrolled study

Dr Harshda Mahajan1 个研究点 分布在 1 个国家目标入组 105 人开始时间: 2024年10月21日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
105
试验地点
1
主要终点
Plaque index, Gingival Index, Probing pocket depth reduction

研究概览

简要总结

Patients with stage I, II, and III periodontitis with 3 sites with pocket depth >4mm each in separate quadrants will be randomly selected for each of the 3 groups. The Moringa Oleifera gel, Placebo Gel, and Chlorhexidine gel will be given according to the groups. Baseline records will be taken and scaling and root planing will be performed. Upon completion of scaling and root planing patients will be given the above-mentioned interventions according to their groups, and then patients will be assessed at 1 week, 1 month, 3 months, 6 month intervals and measurements will be recorded for plaque index, gingival index, probing pocket depth, clinical attachment loss and then results will be drawn and published.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
21.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients with generalized periodontitis stage I, II, III according to 2018 AAP/EFP classification of periodontal and peri-implant diseases with minimum 3 sites in separate quadrants.
  • Patients in age group of 21 to 60 years of either sex.
  • Patients with atleast 20 natural teeth.
  • patient ready to give written informed consent.

排除标准

  • 1.Medically compromised patients.
  • Patients on antibiotic or antimicrobial therapy in past 6 months.
  • smokers and smokeless tobacco users.
  • Patients who have received periodontal treatment in past 6 months.
  • Pregnant woman and lactating woman.
  • Patients allergic to any material used in the study.

结局指标

主要结局

Plaque index, Gingival Index, Probing pocket depth reduction

时间窗: 1 Week, 1 Month, 3 Months, 6 Months

次要结局

  • Clinical Attachment loss(1 Week, 1 Month, 3 Months, 6 Months)

研究者

发起方
Dr Harshda Mahajan
申办方类型
Other [Self sponsered]
责任方
Principal Investigator
主要研究者

Dr Harshda Mahajan

Government dental college and hospital Mumbai

研究点 (1)

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