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临床试验/NCT01356576
NCT01356576已完成不适用

Effect of Hemodialysis Membranes on Platelet Count

Northwell Health1 个研究点 分布在 1 个国家目标入组 99 人开始时间: 2010年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
99
试验地点
1
主要终点
Drop in platelet counts

研究概览

简要总结

The purpose of this study is to determine if there is a drop in platelet count after hemodialysis. Hemodialysis membranes are known to activate complement and cause a drop in platelets and sometimes in white blood cells. The investigators are going to study one of the membranes which is the Fresenius Optiflux® to check if it causes a drop in platelets.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients on Hemodialysis for >=6 months

排除标准

  • Hematological Cancers
  • Myelodysplastic syndromes
  • Baseline thrombocytopenia
  • Acute infections (patients on antibiotics)
  • Patients with Immune thrombocytopenic purpura (ITP)/Thrombotic thrombocytopenic purpura (TTP)
  • Liver disease

结局指标

主要结局

Drop in platelet counts

时间窗: 90 minutes through hemodialysis and immediately after finishing hemodialysis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Edward Epstein

M.D.

Northwell Health

研究点 (1)

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