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临床试验/NCT04943107
NCT04943107Unknown不适用

Effect of Antihypertensive Drugs on Glaucoma Patients

Second Affiliated Hospital, School of Medicine, Zhejiang University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2021年5月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
200
试验地点
1
主要终点
retinal nerve fiber layer thickness

研究概览

简要总结

It has been reported that among Asian non-glaucomatous, antihypertensive medications were associated with retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness. In order to explore whether antihypertensive medications would influence the neuropathy among glaucomatous population, we designed a cross-sectional observational study to analyze the retinal status among glaucoma patients with use of antihypertensive medication.

详细描述

we designed a cross-sectional obeservational study to analyze the retinal status among glaucoma patients with use of hyertensive medication.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age no less than 18 years
  • best corrected visual acuity better than decimal 0.3

排除标准

  • secondary glaucoma
  • secondary hypertension
  • glaucoma-related operation history
  • pregnancy or lactation period
  • uncooperative with retinal examination
  • severe opacity with refracting media in eye
  • severe retinal diseases and neuropathy
  • congenital retinal optic nerve abnormality
  • other systemic diseases that influence hypertension and glaucoma assessment

结局指标

主要结局

retinal nerve fiber layer thickness

时间窗: within 3 months from recruitment

retinal nerve fiber layer thickness measured by optical coherence tomography

次要结局

未报告次要终点

研究者

发起方
Second Affiliated Hospital, School of Medicine, Zhejiang University
申办方类型
Other
责任方
Sponsor

研究点 (1)

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