ISRCTN76742797已完成不适用
Short Pulse AntiRetroviral Therapy At human infection immunodeficiency virus (HIV) seroConversion: a Multicentre randomised trial of therapeutic intervention at primary HIV-1 infection
Imperial College London (UK)0 个研究点目标入组 360 人开始时间: 2005年7月22日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 360
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Patients of both sexes will be eligible for screening if they:
- •1. Have reached the age of consent in their country for participating in a clinical study
- •2. Are confirmed PHI by at least one of following criteria:
- •a. HIV positive antibody test within six-months of an HIV negative antibody test (randomisation must take place within six months of previous negative test)
- •b. HIV antibody negative with positive Reverse Transcription Polymerase Chain Reaction (RT-PCR)
- •c. Test 'incident' at low level (less than 0.6) using detuned assay (must be subtype B)
- •d. Equivocal HIV antibody test supported by a repeat test within a two-week period showing a rising optical density
- •e. Have clinical manifestations of symptomatic HIV seroconversion illness supported by antigen positivity and less than four bands positive on Western Blot
- •3. Able and willing to give written informed consent
排除标准
- •Patients will not be eligible for screening if:
- •1. Pregnant
- •2. Unlikely to comply with protocol, and in particular adhere to therapeutic regimen
- •3. Likely to use narcotics during the study period
- •4. Antiretroviral therapy is indicated
- •5. Antiretroviral therapy is contraindicated
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