Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block Versus Erector Spinae Plane Block in Open Nephrectomy. Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- The total amount of morphine consumption in (mg)
研究概览
简要总结
Our aim is to measure the efficacy of rhomboid intercostal subserratus plane block and erector spinae plane block in patients undergoing open nephrectomy
详细描述
Open nephrectomy incision is associated with a high incidence of intense immediate postoperative pain and chronic pain the months following surgery. Regional anesthesia techniques are commonly recommended for pain management in open nephrectomy as they decrease parenteral opioid requirements and improve patient satisfaction. Rhomboid intercostal subserratus plane block (RISS) is considered a novel approach for chest wall and upper abdominal analgesia, initially showed promising results, first reported in 2016. Erector Spinae Plane block (ESB), was initially described in 2016 for analgesia in thoracic neuropathic pain. It has also been widely used in both adults and children at different levels for different indications. Epidural analgesia is the gold standard for perioperative analgesia in open surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Type of surgery; open nephrectomy.
- •Physical status ASA II, III.
- •Body mass index (BMI): > 20 kg/ m2 and < 35 kg/ m2.
排除标准
- •Patient refusal.
- •Local infection at the puncture site.
- •Severe respiratory or cardiac disorders.
- •Advanced liver or kidney disease.
- •History of psychological disorders and/or chronic pain.
- •Contraindication to regional anesthesia e.g. local sepsis, pre- existing peripheral neuropathies and coagulopathy.
- •Patients with known sensitivity or contraindication to amide local anesthetics used in the study.
结局指标
主要结局
The total amount of morphine consumption in (mg)
时间窗: first 24 hours postoperatively.
amount of morphine in mg consumed in 1st 24 hours
次要结局
- Change in heart rate in (beat/min)(From just before induction till 24 hours post operatively)
- Time of first request of analgesia(first 24 hours postoperatively)
- Numeric Pain Rating Scale(first 24 hours postoperatively)
- Nausea and vomiting Scores(first 24 hours postoperatively)
- Total amount fentanyl in (microgram)(intra operative duration)
- Change in mean arterial blood pressure in (mmHg)(From just before induction till 24 hours post operatively)
研究者
Ahmed Mahmoud Saad
Assistant Lecturer of Anesthesia
Cairo University