Construction and Evaluation of Clinical Prediction Model of In-stent Restenosis After Percutaneous Coronary Intervention by Pericoronary Fat Attenuation Index and Radiomics Characteristics
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 126
- 试验地点
- 1
- 主要终点
- Fat attenuation index (FAI)
研究概览
简要总结
This study aims to investigate the predictive value of fat attenuation index (FAI) and related radiomics characteristics of pericoronary fat in patients after percutaneous coronary intervention (PCI) for the occurrence of in-stent restenosis (ISR) during the follow-up period (9 to 24 months). The results of this study are expected to provide an early assessment of the inflammation around the coronary lesion segment in patients after PCI, and provide a basis for early targeted intensive drug therapy in clinical practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with coronary heart disease who have undergone PCI;
- •Patients followed up coronary angiography 9 to 24 months after PCI;
- •Patients received chest CT examination during inpatient/outpatient follow-up;
排除标准
- •Patients with diseases of the immune system;
- •Patients with history of tumor diseases;
- •Patients with chronic/acute infectious diseases;
- •Image quality is not sufficient for analysis;
结局指标
主要结局
Fat attenuation index (FAI)
时间窗: 2022.8.15-2023.8.14
The pericoronary FAI was defined as the mean CT attenuation of the pericoronary adipose tissue (-190 to -30 HU). Peri-stent FAI was measured around the stent segment of all 3 major epicardial coronary vessels.
次要结局
未报告次要终点