Role of Spectrophotometer in Early Prediction of Weaning Induced Cardiac Dysfunction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- accuracy of change PVI in detecting volume responsiveness
研究概览
简要总结
Weaning induced cardiac dysfunction is a common cause of weaning failure in critically ill patients. plethysmography variability index (PVI) is a non-invasive, real-time, and automated parameter for evalu¬ating fluid responsiveness.
By proving the validity of (PVI) in predicting successful spontaneous breathing trial Massimo can be used an easy noninvasive method that help in deciding the right time for weaning.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Intubation and mechanical ventilation
- •Fulfilling criteria for extubation
- •Fraction inspired oxygen less than 50%
排除标准
- •a. Hemodynamic instability b. b. tracheostomy
结局指标
主要结局
accuracy of change PVI in detecting volume responsiveness
时间窗: 1 hour
accuracy of change PVI in detecting volume responsiveness through measuring limits of agreement , Bias and correlation between PVI and a standard method of measurement which left ventricular outflow tract velocity time integral
次要结局
- Sensitivity of trend of changes in hemoglobin by Massimo to detect WIPO and(1 hour)
- time in minutes between rise of hemoglobin and clinical diagnosis of WIPO(1 hour)
研究者
Amr Fouad
Assistant professor of anesthesia, intensive care and pain management
Ain Shams University