临床试验/NCT03535987

NCT03535987已完成不适用

Pilot Cohort Study of Rb-82 Myocardial PET Imaging to Evaluate Coronary Microvascular Dysfunction in Men With Prostate Cancer Receiving Androgen-Deprivation Therapy

Abramson Cancer Center at Penn Medicine1 个研究点分布在 1 个国家目标入组 18 人开始时间: 2018年1月19日最近更新: 2024年11月19日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Abramson Cancer Center at Penn Medicine
入组人数: 18
试验地点: 1
主要终点: number of subjects who successfully complete Rb-82 myocardial PET Imaging assessments

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

To determine the feasibility of using myocardial PET imaging as a means to assess cardiovascular risk in men with prostate cancer planned for androgen- deprivation therapy with external beam radiation therapy.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 51 Years 至 —（Adult, Older Adult）
性别: Male
接受健康志愿者: 否

入选标准

•Either clinically localized prostate cancer or biochemically-recurrent prostate cancer patients who are planned for at least 6 months ADT with a GnRH agonist and curative-intent radiation therapy per their oncologic providers.
•Over 50 years of age. Calculated 10-year Framingham General Cardiovascular Risk Score of ≥10% at the time of planned initiation of ADT.
•Patients must be able to read and understand English.
•Participants must sign the informed consent form.

排除标准

•Prior treatment with GnRH agonist therapy.
•History of active asthma or other reactive airway disease.
•Ischemic cardiac event (myocardial infarction, unstable angina) within the preceding 6 months.

结局指标

主要结局

number of subjects who successfully complete Rb-82 myocardial PET Imaging assessments

时间窗: 12-18 months

次要结局

未报告次要终点

研究者

发起方

Abramson Cancer Center at Penn Medicine

申办方类型

Other

责任方

Sponsor

研究点 (1)

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