Dietary Induced Thermogenic Differences After Consumption of an Unrefined Meal, a Gluten-free Meal, and a Highly Processed Meal
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 主要终点
- Thermic Effect of Meals (TEM) also known as Postprandial Thermogenesis
研究概览
简要总结
This study will investigate the acute effect of three isocaloric meals varying in level of food processing, including a whole foods, gluten-free, and highly processed meal on energy metabolism and blood glucose in 8-12 young adult, normal weight females. A secondary aim of this proposed study is to compare palatability, satiety, and perceived energy ratings among highly processed, unrefined, and gluten-free unrefined isocaloric meals.
详细描述
A shift towards a diet containing large quantities of highly processed foods is believed to be a major contributor to the trends in obesity. The degree of processing of foods often affects the nutritional content of the constituents. A reduction in macromolecular complexity allows for an increased rate of digestion, meaning that the body does not have to work as hard to metabolize high processed food products. Thus, the purpose of this study is to investigate the effect on energy metabolism and blood glucose after the consumption of an unrefined, whole foods meal versus two highly processed food meals, including a common Western style meal and gluten-free meal in 8-12 young adult, normal weight females. A secondary aim of this proposed study is to compare palatability, satiety, and perceived energy ratings among highly processed, unrefined, and gluten-free unrefined isocaloric meals. It is hypothesized that an unrefined meal will induce a greater postprandial thermogenic response and a smaller blood glucose response than a highly processed or gluten-free meal. Additionally, it is hypothesized that a highly processed foods meal will be considered more palatable than an unrefined or gluten-free meal.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 24 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy females between the ages of 18 and 24 years that have BMIs that fall in the range of 18.5 kg/m2 to 28 kg/m2.
排除标准
- •Those with a history of celiac disease or other food allergies, metabolic disease or heart disease.
结局指标
主要结局
Thermic Effect of Meals (TEM) also known as Postprandial Thermogenesis
时间窗: TEM; 45-60; 105-120; and 165-180 minutes after meal ingestion
The total amount of calories burned after each meal will be measured using indirect calorimetry with the ventilated hood technique. Specifically, the thermic effect of each meal will be measured for a total of three hours at 45 minute intervals for 15 minutes at a time (45-60; 105-120; and 165-180 minutes)
次要结局
- Blood Glucose Response(Baseline line 0 minutes, and 60, 120, 180 minutes postprandial)
- Heart Rate(Baseline 0 minutes, 60, 120, and 180 minutes postprandial)
- Change in Hunger and Palatability Scores and Energy Level(Baseline 0 minutes, and 60, 120, 180 minutes postprandial)
- Blood Pressure(Baseline 0 minutes, 60, 120, and 180 minutes postprandial)
