ACTRN12613000594729招募中未知
Study comparing differences in fibroblast growth factor 23 and other markers of bone turnover in men with various iron store states of iron overload, iron deficiency and normal iron stores.
Associate Professor Emily Hibbert0 个研究点目标入组 140 人开始时间: 2013年5月27日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 140
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35 Years 至 o limit(—)
- 性别
- Male
入选标准
- •The study population will comprise males of age 35 years or greater who meet one of the following criteria:
- •1.iron overload due to haemochromatosis with ferritin > 300microg/l, the upper limit of the reference range or
- •2.normal iron studies
- •3.iron deficiency with ferritin < 30 microg/l ie. below the lower limit of the reference range
排除标准
- •1.Intercurrent proven evidence of cancer – as this will affect ferritin levels and interpretation and may alter FGF 23
- •2.Active infection- will affect ferritin levels and interpretation and may alter FGF 23
- •3.Chronic kidney disease with eGFR< 50 - as eGFR drops, FGF23 levels rise rapidly
- •4.Current glucocorticoid use,
- •5.Hypercalcaemia
- •6.Vitamin D deficiency with 25OH vitamin D level < 25 nmol/l
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