PACTR201810909649406尚未招募未知
Could intraoperative magnesium sulphate protect against postoperative cognitive impairment?
未提供0 个研究点目标入组 80 人开始时间: 2018年10月11日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 80
研究概览
简要总结
intraoperative magnesium sulphate has a protective effect against developing postoperative cognitive dysfunction and reduce the serum level of S100B; the marker of neuronal degeneration
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 19 Year(s) 至 44 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients who are candidate for elective laparoscopic cholecystectomy
- •2.Patients should have the ability to read, write and do simple calculations
- •3.All the participants will be required to offer a written informed con¬sent
排除标准
- •1.Patient subjected to gross hemodynamic or ventilatory fluctuations during the operation
- •2.Patient who developed postoperative shock or major bleeding
- •3.Patient with a history of neurodegenerative disease
- •4.Patients with concomitant medical or metabolic illness known to affect cognition
- •5.Patients with evidence of concomitant cerebrovascular stroke
- •6.Patient with a history of major head trauma
- •7. Patient with a history of epileptic fits in the last two years
- •8.Patient with a history of serious hearing or visual impairment
- •9.Patients with MRI brain showing structural lesion
- •10.Patients with a history of exposure to drug, toxic substances, alcohol, industrial agents, heavy metals, or any substance known to affect cognition.
研究者
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