Clinical Outcomes of Bilateral Uterine Artery Ligation During the Cesarean Delivery of Twins: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- mean Blood loss after placental separation
研究概览
简要总结
Objective to assess the effectiveness of prophylactic bilateral uterine artery ligation (BUAL) in reducing the incidence of postpartum hemorrhage during cesarean delivery among women with twin pregnancy
详细描述
A randomized clinical trial at Aswan University Maternity Hospital, Egypt. Women with twin pregnancy undergoing scheduled or emergency cesarean were randomized into two groups. In the BUAL group, women underwent BUAL before placental delivery; in the control group, women had cesarean delivery without BUAL. The primary outcome was the estimated blood loss during a cesarean
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
open label randomized controlled study
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women undergoing cesarean section
- •twin pregnancy
排除标准
- •Placenta previa.
- •Ante-partum hemorrhage.
- •patient refuse to participate
研究组 & 干预措施
study group
patients with twin pregnancy undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.
干预措施: bilateral uterine artery ligation (Procedure)
study group
patients with twin pregnancy undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.
干预措施: Oxytocin (Drug)
control group
patients with twin pregnancy undergoing cesarean section received oxytocin only.
干预措施: Oxytocin (Drug)
结局指标
主要结局
mean Blood loss after placental separation
时间窗: 30 minutes
by using weight of soaked towels (weight of soaked towel - weight of dry towel) and amount of blood in suction set
次要结局
- Number of Participants with postpartum hemorrhage(12 hours)
- The number of participant needed for blood transfusion(24 hours)
研究者
hany farouk
A Professor
Aswan University Hospital