ACTRN12622000182796进行中(未招募)未知
The feasibility of a personalized approach to venous thromboembolism prophylaxis in heavier critically ill patients.
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中(未招募)
- 入组人数
- 53
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit(—)
- 性别
- All
入选标准
- •I. Adult patients greater than or equal to 18 years of age
- •II. Admitted to RMH ICU
- •III. Admission weight recorded as greater than or equal to 100 kg
- •IV. Suitable to receive VTE chemoprophylaxis with enoxaparin (a Low Weight Molecular Heparin)
排除标准
- •I. Renal impairment that would cause a reduction in chemoprophylaxis dosing (eGFR < 30 ml/min).
- •II. Admitted after cardiac- neuro- or spinal surgery
- •III. Pregnancy
- •IV. Abnormal baseline coagulation (INR >1.5 or APTT >60 sec or platelets <50 × 109/L)
- •V. Require therapeutic anti-coagulation
- •VI. Treating intensivist believes either a fixed dose (40mg BD) OR weight-based dynamic adjustment dosing regimen is required for that patient.
- •VII. Received > 3 doses of enoxaparin in this ICU admission
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