Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Clinical improvement of Alopecia Areata After treatment As assessed by Severity of Alopecia tool (SALT) score
研究概览
简要总结
Alopecia Areata is a common condition. This study investigated the efficacy of calcipotriol versus Narrow Band Ultraviolet B in treatment of Alopecia areata and their effects on serum vitamin D3 levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 14 Years 至 40 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Alopecia Areata of scalp
排除标准
- •Other causes of alopecias including scarring alopecia, androgenic alopecia, telogen effluvium autoimmune diseases, pregnant and lactating females
研究组 & 干预措施
Group II
干预措施: Narrow Band UVB (Device)
Group I
干预措施: Calcipotriol (Drug)
Group I
干预措施: vitamin D3 level (Diagnostic Test)
Group II
干预措施: vitamin D3 level (Diagnostic Test)
Group III
干预措施: Calcipotriol (Drug)
Group III
干预措施: Narrow Band UVB (Device)
Group III
干预措施: vitamin D3 level (Diagnostic Test)
Group IV
干预措施: vitamin D3 level (Diagnostic Test)
结局指标
主要结局
Clinical improvement of Alopecia Areata After treatment As assessed by Severity of Alopecia tool (SALT) score
时间窗: 3 months
calculation of SALT score before and after treatment
Improvement of serum Vitamin D levels in (ng/ml) after treatment
时间窗: 3 months
measurement of serum vitamin D before and after treatment
次要结局
未报告次要终点
研究者
Moustafa A. El Taieb
Head of Dermatology, Venereology and Andrology Department, Ass. Prof. Principal Investigator
Aswan University Hospital