Assessment of the effect of topical calcitriol on Chronic Rhinosinusitis
Phase 2
Recruiting
- Conditions
- chronic rhinosinusitis with and without polyps.chronic sinusitis
- Registration Number
- IRCT201705173186N11
- Lead Sponsor
- Vice chancellor for research, Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
all patients older than 18 years with the diagnostic criteria for chronic rhinosinusitis with polyposis based on the EPOS 2012 criteria. Exclusion criteria: smoking; sensitivity to vitamin D3; pregnancy; use of systemic steroids in last month; immunosuppressive drugs; history of any endocrine disease, malignancy, acute rhinosinisitis during study, surgery for rhinosinusitis, complication of rhinosinusitis, calcification of soft tissue and hypercalcemia.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Chronic rhinosinusitis. Timepoint: Before intervention and 1and 3 months after intervention. Method of measurement: VAS, SNOT22 and Lund Kennedy scoring.
- Secondary Outcome Measures
Name Time Method Drug adverse effect such as nasal irritation. Timepoint: during study period. Method of measurement: questionnaire.