IRCT2017053034222N1招募中3 期
Effect of Calcitriol supplementation on the severity of fatty liver, inflammatory and metabolic biomarkers in patients with non-alcoholic fatty liver with different genotypes of vitamin D receptor
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 160
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •Age between 18- 60 years
- •Presence of NAFLD diagnosed by Fibroscan elastography
- •Increased alanine transaminase (> 40 U/L)
- •BMI below 35
排除标准
- •Alcohol consumption greater than 20 g per day
- •pregnancy; lactation
- •viral or autoimmune hepatitis
- •hereditary hemochromatosis
- •Wilson's disease
- •a1-antitripsin deficiency
- •malabsorption syndromes
- •consumption of hepatotoxic drugs
- •high doses of synthetic estrogens
- •hypothyroidism and Cushing's syndrome
- •Serum calcium greater than 10.6 mg/dl
- •history of kidney stones; renal failure
- •intake of vitamin D, vitamin E and calcium supplements
研究者
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