Evaluation of the effect of calcitriol supplementation on diabetes control and its complications in hyperlipidemic patients with type 2 diabetes mellitus, Shiraz, 2009
Phase 2
- Conditions
- Diabetes mellitus.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT138806282480N1
- Lead Sponsor
- Shiraz university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Age>30 years, Hb.A1C<8%, FBS<160 mg/dl, Serum Calcium < 10.5 mg/dl, LDL<150 mg/dl, normal liver and kidney function, no history of kidney stone, not taking insulin therapy, no hypercalcemia was seen.
Exclusion criteria: using vitamin D supplement, pregnancy, smoking, UVB exposure with therapeutic goals, acute kidney or liver disease, hypercalcemia, hyperparathyroidism.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FBS. Timepoint: 3 times, with 1.5 month intervals. Method of measurement: Auto analyser.;Serum insulin. Timepoint: 3 times, with 1.5 month intervals. Method of measurement: with Eliza kit, Monobind.
- Secondary Outcome Measures
Name Time Method Hb.A1C. Timepoint: before and after intervention. Method of measurement: Nycocard kit.;MDA (Malondialdehyde). Timepoint: before and after intervention. Method of measurement: spectrophotometery.;Lipid profile. Timepoint: 3 times, with 1.5 month intervals. Method of measurement: auto analysor.;Interleukin 1. Timepoint: 2 times with 3 month intervals. Method of measurement: eliza kit.;Interleukin 6. Timepoint: 2 times with 3 month intervals. Method of measurement: eliza kit.;Interleukin 18. Timepoint: 2 times with 3 month intervals. Method of measurement: eliza kit.;CRP. Timepoint: 2 times with 3 month intervals. Method of measurement: eliza kit.