IRCT20200218046533N1
Recruiting
Phase 2
The Evaluation of the Efficacy of Calcitriol Compared to Calcitriol plus Cinacalcet in the Treatment of Severe Secondary Hyperparathyroidism in Hemodialysis Patients Referred to Dialysis Centers in Gorgan
Gorgan University of Medical Sciences0 sites70 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Gorgan University of Medical Sciences
- Enrollment
- 70
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Aged 18 years and more;
- •Dialysis for at least 3 months;
- •iPTH levels above 800 pg/dL (severe secondary hyperparathyroidism);
- •Do not take medications that have drug interactions such as flecainide, thioridazine, tricyclic antidepressants due to the effect of Cinacalcet on the P\-450 cytochrome;
- •No hypersensitivity reaction to the drugs used in the study;
- •No liver disease;
- •Calcium levels \> 8\.4 mg/dL.
Exclusion Criteria
- •Any evidence of cancer in different parts of the body;
- •Side effects of the medications used during the study period;
- •Diseases causing hypercalcemia;
- •History of parathyroidctomy;
- •Presence of parathyroid adenoma (to be confirmed by parathyroid scan);
- •Pregnant mothers or lactating women or females of childbearing age who do not currently use contraception.
Outcomes
Primary Outcomes
Not specified
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