Effects of exercise intensity on non-motor symptoms in early Parkinson’s disease: randomized, controlled, single-blinded, pilot study

Inha University Hospital0 个研究点目标入组 33 人开始时间: 待定最近更新: 2023年8月1日

试验速览

暂无简介。

•1) Patients who were diagnosed with Parkinson's disease based on the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria
•2) Patients who were aged between 50 and 80
•3) Patients with Hoehn and Yahr stage 1 or 2
•4) Patients with the disease duration of less than 5 years
•5) Patients who had a score = 1 in the MDS-UPDRS part 1
•6) Patients who did less than the recommended aerobic exercise proposed by the American College of Sports Medicine (ACSM) (ex. vigorous exercise done <3 times per week, 20 min per session; or moderate exercise done <5 times per week, 30 min per session)
•7) Patients who were on stable dopaminergic pharmacotherapy over more than 3 months

•1) Patients with neurological, orthopedic, or cardiac comorbidities that make them unfit to do aerobic exercise
•2) Patients who were unable to complete questionnaires due to cognitive impairment
•3) Patients on antipsychotics
•4) Patients who have symptoms or signs suggesting atypical or secondary parkinsonism (ex. cerebellar signs, supranuclear gaze palsy, apraxia, prominent autonomic failure, or other cortical signs; multiple strokes with stepwise progression of symptoms)
•5) Patients who were unavailable for more than 10% of the study period

发起方