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临床试验/NCT01644916
NCT01644916已完成不适用

"Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity"

National University of Singapore2 个研究点 分布在 1 个国家目标入组 295 人开始时间: 2012年8月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
295
试验地点
2
主要终点
HADS score

研究概览

简要总结

Chronic obstructive pulmonary disease (COPD) stands out among chronic diseases with its high and rising prevalence and mortality, poor quality of life, high re-hospitalization rates and societal burden of care. Current therapeutic and management practices are generally met with limited success. Research in recent years have highlighted the high level of psychiatric co-morbidity in COPD patients, and the major prognostic significance of anxiety/depression in COPD outcomes such as re-hospitalization, smoking cessation, quality of life, and survival. This suggests that addressing psychiatric and psycho-social aspects of care prominent in COPD patients may have strongly positive impact on outcomes, but the available evidence of effectiveness is limited.

The primary aim of the proposed research is to evaluate the effectiveness of a holistic disease management paradigm of psychiatric liaison consultation (CL) that integrates psychiatric and respiratory care to improve outcomes for COPD patients. This integrated psychiatric consultation liaison (IPCL) management paradigm includes the routine screening and structured collaborative care of anxiety and major depressive symptoms and depressive/anxiety disorder in COPD patients. We postulate that the IPCL care paradigm would reduce mood symptoms, increase smoking quit rates, reduce symptom burden and functional disability, and improve quality of life, while reducing rehospitalization, emergency department (ED) and unscheduled physician visits. A secondary aim is to evaluate its cost effectiveness by concurrently collecting resource utilization data.

详细描述

Specific Aims

The aim of the proposed research is to evaluate the effectiveness of a holistic disease management paradigm of) that integrates psychiatric and respiratory care (Integrated Psychiatric Consultation Liaison, IPCL) that addresses the high level of psychiatric co-morbidity in COPD patients to improve COPD outcomes.

Methods

Patient population Inpatients and specialist outpatients with established clinical diagnosis of chronic obstructive pulmonary disease (COPD).

Settings

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
55 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Inpatients and specialist outpatients from: NUHS, SGH, CGH, SLH and AH.
  • Clinical diagnosis of chronic obstructive pulmonary disease (COPD) based on history, physical examination, spirometry, measurement of arterial blood gases, and chest radiographs, that meets the criteria for COPD as defined in the Global Initiative for Chronic Obstructive Lung Disease (GOLD).
  • COPD patients include cases of all grades of severity, and co-morbidity, without restriction.
  • Participants provide written informed consent.

排除标准

  • Known diagnosis of a psychiatric disorder that is under treatment.
  • Terminally ill COPD patients who are unable to complete baseline assessments.

研究组 & 干预措施

Usual control

Other

Usual control will be provided with usual standard management of COPD and psychiatric comorbidities.

干预措施: Usual control (Procedure)

Integrated care

Other

Integrated care will be provided with integrated care management.

干预措施: Integrated care (Procedure)

结局指标

主要结局

HADS score

时间窗: over 12 months

Anxiety and depression symptoms and diagnosis

次要结局

  • Resource use and direct costs of care(over 12 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

A/Prof Ng Tze Pin

Research Director

National University of Singapore

研究点 (2)

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