The Possible Association Between Bisphenol A, Paraben Exposure and Type 2 Diabetic Adult Patients.
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Bisphenol A and paraben detection in urine samples of diabetic (n=50) and non diabetic persons (n=50)
研究概览
简要总结
The aim of this study is to evaluate the association between BPA , paraben levels and type 2 DM patients
详细描述
The first phase of the study will include a questionnaire :
- The cases and control will be asked about demographic information such as residence, age, education, and occupation.
- History of discovery of diabetes.
- Exposure to products and materials such as polycarbonate plastics, cosmetics and beverages containing bisphenol A and paraben and it will be evaluated through exposure sheet through asking about dietary exposure, Environmental exposure and medical exposure.
Then clinical evaluation including:
- Full clinical examination will be performed for cases and control.
- Anthropological data:
their weights, heights and waist circumference will be measured. The body mass index (BMI) will be calculated by weight (kg)/height (m)2 formula.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult patients ( 18 y or elder).
排除标准
- •Type 1 DM
- •Less than 18 y
- •History of chronic diseases such as liver failure, cardiac patients......etc
研究组 & 干预措施
Case group
50 cases with type 2 DM.
干预措施: HPLC (Device)
Control group
50 subjects not diabetics.
干预措施: HPLC (Device)
结局指标
主要结局
Bisphenol A and paraben detection in urine samples of diabetic (n=50) and non diabetic persons (n=50)
时间窗: Baseline
Evaluation of bisphenol A and Paraben detection in urine samples from type 2 diabetic adult patients compared with non diabetic persons using HPLC
次要结局
未报告次要终点
研究者
Ahmed Fathy Hussein Awad
Assistant lecturer of forensic medicine and clinical toxicology
Cairo University