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临床试验/NCT04042636
NCT04042636已完成不适用

Epidemiological Patterns for Early Onset and Late Onset Bacteremia After Trauma

Asan Medical Center1 个研究点 分布在 1 个国家目标入组 859 人开始时间: 2011年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
859
试验地点
1
主要终点
Risk factor for bacteremia after trauma

研究概览

简要总结

Presence of pelvic and liver injury on arrival in ED, gastrointestinal tract perforation and massive transfusion within the first 24 hours after trauma appear a significant risk factor for bacteremia. Scoring with the ISS, intra-abdominal and pelvic injury and presence of transfusion and shock at admission to ED appears a useful tool for identifying trauma patients at increased risk of bacteremia.

详细描述

Purpose: Bacteremia is a major nosocomial infection problem in view of its high mortality. Bacteremia occurs in trauma patients frequently and increases a morbidity and mortality. The aim of this study was to identify risk factors and to describe epidemiological patterns for early onset (EOB) and late onset (LOB) bacteremia after trauma.

Methods: All trauma patients admitted to surgical intensive care unit (SICU) and general ward (GW) from January 2011 to December 2015 were retrospectively enrolled. The following information was collected for each patient and recorded in a computer database: demography, severity of trauma according to the Injury Severity Score (ISS) and each abbreviated injury score (AIS), severity of coma according to the Glasgow Coma Scale (GCS), presence of shock and transfusion. Early onset bacteremia was defined as EOB when onset occurred within 7 days after trauma, and late onset bacteremia was defined as LOB when appearing after 7 days from trauma.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The patients who admitted to intensive care unit (ICU) or general ward (GW) through the emergency department after trauma were studied

排除标准

  • Patients who arrived on dead-on arrival

结局指标

主要结局

Risk factor for bacteremia after trauma

时间窗: 5 years

finding fisk factor for bacteremia in traumatic patients

次要结局

  • Etiology of bacteremia after trauma(5 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Suk-Kyung

professor

Asan Medical Center

研究点 (1)

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