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临床试验/NCT03565523
NCT03565523已完成不适用

The Effect of Dietary Nitrate Supplementation on Linear Running Sprint Performance, Agility and Vertical Jump Performance in a Rested and Fatigued State

PepsiCo Global R&D0 个研究点目标入组 32 人开始时间: 2016年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
32
主要终点
Linear running sprint time

研究概览

简要总结

Dietary nitrate (NO3-) supplementation has been shown to improve skeletal muscle contractility and fatigue resistance, particularly in fast-twitch (type II) muscle fibers. Furthermore, NO3- supplementation has been shown to speed reaction time. Taken together, these findings suggest that NO3- ingestion may be ergogenic during all-out sprint running and reactive agility tasks. Moreover, increasing muscle force production at high contraction speeds would be expected to translate into improved muscle power and, subsequently, improved performance in very explosive forms of exercise, such as vertical jumping. Therefore, the purpose of this investigation is to assess the effect of short term (5 days) NO3- supplementation on linear running sprint performance, reactive agility and vertical jump performance in a rested and fatigued state.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Male and female participants in self-reported good general health as assessed by the standard procedures described below and specifically meeting normal blood pressure range (systolic: 100-135, diastolic: 60-90) and body mass index (BMI) range (16.0-29.9)
  • Range of 18-45 years of age
  • Participants must participate in an intermittent exercise based sport (e.g. soccer, rugby, hockey), at a competitive level (i.e. competes in officiated matches/games).
  • Understanding of the procedures to be undertaken as part of the study
  • Willingness to participate in exercise testing and follow supplementation guidelines and other instructions provided by the experimenter
  • Informed, voluntary, written consent to participate in the study

排除标准

  • Known pulmonary, cardiovascular or metabolic disease
  • Food allergies including phenylketonurea (PKU)
  • Current regular use of any dietary supplement (excluding macronutrient based supplements) or previous use of any dietary supplement in the past 6 months that is known to have a lasting effect.
  • Blood donation within 3 months prior to the start of the study
  • Substance abuse within 2 years of the start of the study
  • Any prescription and non-prescription medication which may impact saliva production (antidepressants, diuretics, analgesics, antihistamines, anti-hyper/hypo-tensives, anti-anxiety, appetite suppressants).
  • Current or previous use of phosphodiesterase 5 (PDE5) inhibitors.
  • Participation in another clinical trial within past 4 weeks.

研究组 & 干预措施

Test Beet shot

Experimental

Containing 385 mg nitrate

干预措施: Beetroot (Other)

Placebo beverage

Placebo Comparator

<0.1 mmol nitrate in sucrose solution with beet coloring

干预措施: Placebo beverage (Other)

结局指标

主要结局

Linear running sprint time

时间窗: 5 days

Linear running sprint in a rested and fatigued state

次要结局

未报告次要终点

研究者

申办方类型
Industry
责任方
Sponsor

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